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Moxibac 0.5% Eye Drops 5ml
Moxifloxacin works by inhibiting bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair. By targeting these enzymes, Moxibac effectively prevents bacterial growth and division.
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✅ Description:
Moxibac ophthalmic solution is prescribed for bacterial conjunctivitis caused by susceptible strains of the following organisms:
Aerobic Gram-positive bacteria: Corynebacterium species, Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus warneri, Streptococcus pneumoniae, and Streptococcus viridans group.
Aerobic Gram-negative bacteria: Acinetobacter lwoffii, Haemophilus influenzae, Haemophilus parainfluenzae.
Other organisms: Chlamydia trachomatis.
Intraocular Use: Effective in preventing postoperative bacterial endophthalmitis when administered intraocularly before eye surgery.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects
Ocular Side Effects (1-6% of patients): Conjunctivitis, dry eyes, eye discomfort, decreased vision, keratitis, redness, pain, itching, subconjunctival hemorrhage, and excessive tearing.
Non-Ocular Side Effects (1-4% of patients): Fever, cough, infections, otitis media, sore throat, rash, and rhinitis.
✔️ Dosage & Administration
Eye Drops: Instill one drop into the affected eye, three times daily for 7 days.
✔️ Drug Interactions
No formal drug interaction studies have been conducted with Moxibac ophthalmic solution. However, in vitro studies suggest that Moxibac does not inhibit CYP3A4, CYP2D6, CYP2C9, CYP2C19, or CYP1A2, meaning it is unlikely to interfere with drugs metabolized by these liver enzymes.
✔️ Contraindications
Do not use in patients allergic to Moxifloxacin, other quinolones, or any of the components in this medication.
✔️ Pregnancy & Lactation
Pregnancy:
No well-controlled studies exist in pregnant women.
Use only if the potential benefits outweigh the risks to the fetus.
Lactation:
While Moxifloxacin levels in human milk have not been specifically studied, it is likely excreted in breast milk.
Exercise caution when using during breastfeeding.
✔️ Precautions & Warnings
Risk of Superinfection:
- Prolonged use may lead to overgrowth of resistant organisms, including fungi.
- If a secondary infection occurs, discontinue use and switch to an alternative treatment.
Eye Examination:
- A slit lamp biomicroscopy or fluorescein staining may be needed for proper evaluation.
Contact Lenses:
- Avoid wearing contact lenses while experiencing symptoms of bacterial conjunctivitis.
✔️ Storage Conditions
- Store below 25°C, in a cool, dry place, protected from light.
- Do not freeze.
- Keep out of children's reach.
- Avoid contaminating the dropper tip by not touching any surfaces.
- Discard after one month of opening.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
